Enzymatic Degradation of Chlorodiamino- s -Triazine

Enzymatic degradation of chlorodiamino-s-triazine.

2-Chloro-4,6-diamino-s-triazine (CAAT) is a metabolite of atrazine biodegradation in soils. Atrazine chlorohydrolase (AtzA) catalyzes the dechlorination of atrazine but is unreactive with CAAT. In this study, melamine deaminase (TriA), which is 98% identical to AtzA, catalyzed deamination of CAAT to produce 2-chloro-4-amino-6-hydroxy-s-triazine (CAOT). CAOT underwent dechlorination via hydroxya...

Oxidative Degradation Of Triazine Derivatives

Biodegradation of s-triazine xenobiotics

Biodegradation of xenobiotic compounds is examined with s-triazines as an example and with biological treatment of wastewater containing striazines as an aim. s-Triazines have been termed recalcitrant, but examination of the literature indicates that a potential for biodegradation exists. Ni t rogenl imi ted enr ichment cultures yield organisms able to degrade by-products of the industrial synt...

Degradation of explosive 2,4,6-trinitrotoluene by s-triazine degrading bacterium isolated from contaminated soil.

2,4,6-Trinitrotolene (TNT) is a military explosive and a predominant contaminant of soil and ground water at many sites of TNT production and processing in many countries. TNT is recalcitrant and has been shown to be toxic to aquatic and terrestrial organisms in the environment (Won et al. 1976). TNT can be degraded, mineralized, or conjugated into more complex products by a variety of microorg...

Rapid Enzymatic Degradation

The effect of plasma on degradation of human growth hormonereleasing hormone (GRH) was examined in vitro and in vivo using high performance liquid chromatography (HPLC), radioimmunoassay (RIA), and bioassay. When GRH(1-44)-NH2 was incubated with human plasma, the t1/2 of total GRH immunoreactivity was 63 min (RIA). However, HPLC revealed a more rapid disappearance (t1/2, 17 min) ofGRH(144)-NH2 ...